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doi:10.22028/D291-38511
Titel: | Identification of Neural Mechanisms in First Single-Sweep Analysis in oVEMPs and Novel Normative Data |
VerfasserIn: | Hecker, Dietmar J. Scherer, Hans Schönfeld, Uwe Jerono, Laura Koch, Armand Rink, Anna-Katharina Schulte-Goebel, Lisa Linxweiler, Maximilian Fousse, Mathias Bozzato, Alessandro Schick, Bernhard |
Sprache: | Englisch |
Titel: | Journal of Clinical Medicine |
Bandnummer: | 11 |
Heft: | 23 |
Verlag/Plattform: | MDPI |
Erscheinungsjahr: | 2022 |
Freie Schlagwörter: | oVEMPs bone-conducted n10 amplitude and latency single sweeps synchronization novel algorithms efferent mechanism |
DDC-Sachgruppe: | 610 Medizin, Gesundheit |
Dokumenttyp: | Journalartikel / Zeitschriftenartikel |
Abstract: | Background: Bone-conducted (BC) VEMPs provide important tools for measuring otolith function. However, two major drawbacks of this method are encountered in clinical practice—small n10 amplitude and averaging technique. In this study, we present the results of a new VEMP setup measuring technique combined with a novel single-sweep analysis. Methods: The study included BC oVEMP data from 92 participants for the evaluation of normative data using a novel analysis technique. For evaluating test-retest reliability, the intraclass correlation coefficient (ICC) was used. Results: We found significant n10 amplitude differences in single-sweep analyses after the first and second measurements. Thereby, mathematical analyses of the head movement did not show any differences in the first or second measurements. The normative n10 amplitude was 20.66 µV with an asymmetric ratio (AR) of 7%. The new value of late shift difference (LSD) was 0.01 ms. The test retest-reliability showed good to excellent ICC results in 9 out of 10 measurements. Conclusions: Our results support a phenomenon in single-sweep analysis of the first stimuli independent of head movement and signal morphology. Furthermore, the values obtained with the new measurement method appear to be more sensitive and may allow an extended diagnostic range due to the new parameter LSD. |
DOI der Erstveröffentlichung: | 10.3390/jcm11237124 |
Link zu diesem Datensatz: | urn:nbn:de:bsz:291--ds-385118 hdl:20.500.11880/34775 http://dx.doi.org/10.22028/D291-38511 |
ISSN: | 2077-0383 |
Datum des Eintrags: | 15-Dez-2022 |
Fakultät: | M - Medizinische Fakultät |
Fachrichtung: | M - Hals-Nasen-Ohrenheilkunde |
Professur: | M - Prof. Dr. Bernhard Schick |
Sammlung: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
Dateien zu diesem Datensatz:
Datei | Beschreibung | Größe | Format | |
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jcm-11-07124-v2.pdf | 1,06 MB | Adobe PDF | Öffnen/Anzeigen |
Diese Ressource wurde unter folgender Copyright-Bestimmung veröffentlicht: Lizenz von Creative Commons