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doi:10.22028/D291-38334
Titel: | Theoretical modelling of competitive microbial range expansion with heterogeneous mechanical interactions |
VerfasserIn: | Maikranz, E. Santen, L. |
Sprache: | Englisch |
Titel: | Physical Biology |
Bandnummer: | 18 (2021) |
Heft: | 1 |
Verlag/Plattform: | IOP Publishing |
Erscheinungsjahr: | 2020 |
Freie Schlagwörter: | range expansion competition biofilm growth Eden model passive mobility cell sorting pushing |
DDC-Sachgruppe: | 500 Naturwissenschaften |
Dokumenttyp: | Journalartikel / Zeitschriftenartikel |
Abstract: | Microbial range expansion experiments provide insight into the complex link between dynamic structure, pattern formation and evolutionary dynamics of growing populations. In this work, we develop a theoretical model in order to investigate the interplay of growth statistics and mechanical interactions which are implemented as division driven pushing and swapping of cells. For the case of the competitive growth of a strongly and a weakly interacting strain we investigate the influence of different mean division times, as well as different mechanical interactions on the development of the colony. Our results show that the susceptibility to cell division induced pushing has a much stronger influence on the structure of the colony than cell sorting towards the colony’s perimeter. Motivated by microbial range expansion experiments of Neisseria gonorrhoeae bacteria, we also consider the influence of mutating cells on the structure of the colony. We show that the outgrowth of the three different strains is strongly influenced by the relative strengths of their mechanical interaction. The experimentally observed patterns are reproduced for mechanical interactions of the mutants, which range between those of the strongly and weakly interacting strain. |
DOI der Erstveröffentlichung: | 10.1088/1478-3975/abcae9 |
URL der Erstveröffentlichung: | http://dx.doi.org/10.1088/1478-3975/abcae9 |
Link zu diesem Datensatz: | urn:nbn:de:bsz:291--ds-383347 hdl:20.500.11880/34592 http://dx.doi.org/10.22028/D291-38334 |
ISSN: | 1478-3975 1478-3967 |
Datum des Eintrags: | 1-Dez-2022 |
Fakultät: | NT - Naturwissenschaftlich- Technische Fakultät |
Fachrichtung: | NT - Physik |
Professur: | NT - Prof. Dr. Ludger Santen |
Sammlung: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
Dateien zu diesem Datensatz:
Datei | Beschreibung | Größe | Format | |
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Maikranz_2021_Phys._Biol._18_016008.pdf | 2,82 MB | Adobe PDF | Öffnen/Anzeigen |
Diese Ressource wurde unter folgender Copyright-Bestimmung veröffentlicht: Lizenz von Creative Commons