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doi:10.22028/D291-38217
Titel: | Impact of Smoking Status on Mortality in STEMI Patients Undergoing Mechanical Reperfusion for STEMI : Insights from the ISACS–STEMI COVID-19 Registry |
VerfasserIn: | De Luca, Giuseppe Algowhary, Magdy Uguz, Berat Oliveira, Dinaldo C. Ganyukov, Vladimir Zimbakov, Zan Cercek, Miha Jensen, Lisette Okkels Loh, Poay Huan Calmac, Lucian Ferrer, Gerard Roura i Quadros, Alexandre Milewski, Marek Scotto D’Uccio, Fortunato von Birgelen, Clemens Versaci, Francesco Ten Berg, Jurrien Casella, Gianni Wong Sung Lung, Aaron Kala, Petr Díez Gil, José Luis Carrillo, Xavier Dirksen, Maurits Becerra-Munoz, Victor M. Lee, Michael Kang-yin Juzar, Dafsah Arifa Joaquim, Rodrigo de Moura Paladino, Roberto Milicic, Davor Davlouros, Periklis Bakraceski, Nikola Zilio, Filippo Donazzan, Luca Kraaijeveld, Adriaan Galasso, Gennaro Arpad, Lux Lucia, Marinucci Vincenzo, Guiducci Menichelli, Maurizio Scoccia, Alessandra Yamac, Aylin Hatice Ugur Mert, Kadir Flores Rios, Xacobe Kovarnik, Tomas Kidawa, Michal Moreu, Josè Vincent, Flavien Fabris, Enrico Martínez-Luengas, Iñigo Lozano Boccalatte, Marco Bosa Ojeda, Francisco Arellano-Serrano, Carlos Caiazzo, Gianluca Cirrincione, Giuseppe Kao, Hsien-Li Sanchis Forés, Juan Vignali, Luigi Pereira, Helder Manzo, Stephane Ordoñez, Santiago Özkan, Alev Arat Scheller, Bruno Lehtola, Heidi Teles, Rui Mantis, Christos Antti, Ylitalo Silveira, João António Brum Zoni, Rodrigo Bessonov, Ivan Savonitto, Stefano Kochiadakis, George Alexopulos, Dimitrios Uribe, Carlos E. Kanakakis, John Faurie, Benjamin Gabrielli, Gabriele Barrios, Alejandro Gutierrez Bachini, Juan Pablo Rocha, Alex Tam, Frankie Chor-Cheung Rodriguez, Alfredo Lukito, Antonia Anna Saint-Joy, Veauthyelau Pessah, Gustavo Tuccillo, Andrea Cortese, Giuliana Parodi, Guido Bouraghda, Mohamed Abed Kedhi, Elvin Lamelas, Pablo Suryapranata, Harry Nardin, Matteo Verdoia, Monica |
Sprache: | Englisch |
Titel: | Journal of Clinical Medicine |
Bandnummer: | 11 |
Heft: | 22 |
Verlag/Plattform: | MDPI |
Erscheinungsjahr: | 2022 |
Freie Schlagwörter: | myocardial infarction smoking paradox percutaneous coronary intervention COVID-19 |
DDC-Sachgruppe: | 610 Medizin, Gesundheit |
Dokumenttyp: | Journalartikel / Zeitschriftenartikel |
Abstract: | The so-called “smoking paradox”, conditioning lower mortality in smokers among STEMI patients, has seldom been addressed in the settings of modern primary PCI protocols. The ISACS– STEMI COVID-19 is a large-scale retrospective multicenter registry addressing in-hospital mortality, reperfusion, and 30-day mortality among primary PCI patients in the era of the COVID-19 pandemic. Among the 16,083 STEMI patients, 6819 (42.3%) patients were active smokers, 2099 (13.1%) previous smokers, and 7165 (44.6%) non-smokers. Despite the impaired preprocedural recanalization (p < 0.001), active smokers had a significantly better postprocedural TIMI flow compared with nonsmokers (p < 0.001); this was confirmed after adjustment for all baseline and procedural confounders, and the propensity score. Active smokers had a significantly lower in-hospital (p < 0.001) and 30-day (p < 0.001) mortality compared with non-smokers and previous smokers; this was confirmed after adjustment for all baseline and procedural confounders, and the propensity score. In conclusion, in our population, active smoking was significantly associated with improved epicardial recanalization and lower in-hospital and 30-day mortality compared with previous and non-smoking history |
DOI der Erstveröffentlichung: | 10.3390/jcm11226722 |
Link zu diesem Datensatz: | urn:nbn:de:bsz:291--ds-382173 hdl:20.500.11880/34505 http://dx.doi.org/10.22028/D291-38217 |
ISSN: | 2077-0383 |
Datum des Eintrags: | 25-Nov-2022 |
Bezeichnung des in Beziehung stehenden Objekts: | Supplementary Materials |
In Beziehung stehendes Objekt: | https://www.mdpi.com/article/10.3390/jcm11226722/s1 |
Fakultät: | M - Medizinische Fakultät |
Fachrichtung: | M - Innere Medizin |
Professur: | M - Prof. Dr. Bruno Scheller-Clever |
Sammlung: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
Dateien zu diesem Datensatz:
Datei | Beschreibung | Größe | Format | |
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jcm-11-06722-v4.pdf | 1,12 MB | Adobe PDF | Öffnen/Anzeigen |
Diese Ressource wurde unter folgender Copyright-Bestimmung veröffentlicht: Lizenz von Creative Commons