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Titel: New Wound Management of Driveline Infections with Cold Atmospheric Plasma
VerfasserIn: Kremer, Jamila
Meinert, Étienne Fasolt Richard Corvin
Farag, Mina
Mueller, Florian
Soethoff, Jasmin Penelope
Karck, Matthias
Schmack, Bastian
Meyer, Anna Lassia
Warnecke, Gregor
Sprache: Englisch
Titel: Journal of Cardiovascular Development and Disease
Bandnummer: 9
Heft: 11
Verlag/Plattform: MDPI
Erscheinungsjahr: 2022
Freie Schlagwörter: left ventricular assist device
wound infection
driveline infection
mechanical circulatory support
cold atmospheric argon plasma
DDC-Sachgruppe: 610 Medizin, Gesundheit
Dokumenttyp: Journalartikel / Zeitschriftenartikel
Abstract: The use of ventricular assist devices as a bridge to transplant or as destination therapy has increased. Wound complications increase morbidity in this cohort. Cold atmospheric plasma is a source of reactive oxygen and nitrogen species and can reduce the microbial load in skin wounds without negative effects on the surrounding tissue. We evaluated our cold atmospheric plasma treatment for LVAD driveline infections in a retrospective single-center study for peri- and postintervention outcome analysis. Between April 2019 and September 2019, 15 male patients were included (5 HVAD, 10 HeartMate III). The wounds were treated for a mean of 368.5 s with a reduction of bacterial load in treated wounds in 60% of patients, regardless of the pathogen. The most common pathogen was staphylococcus aureus (n = 8 patients). There was a significant reduction of the wound scale (scale 2.80 vs. 1.18; p < 0.001) plus a significant reduction in size (16.08 vs. 1.90 cm3 ; p = 0.047). Seven patients (46.6%) were free from any signs of local or systemic infection during 1-year follow-up. Five patients (33%) received a heart transplantation. Cold atmospheric plasma treatment is a potent, safe, and painless adjuvant technique for treating driveline infection without the need for repeating surgical interventions.
DOI der Erstveröffentlichung: 10.3390/jcdd9110405
Link zu diesem Datensatz: urn:nbn:de:bsz:291--ds-382121
hdl:20.500.11880/34496
http://dx.doi.org/10.22028/D291-38212
ISSN: 2308-3425
Datum des Eintrags: 25-Nov-2022
Fakultät: M - Medizinische Fakultät
Fachrichtung: M - Innere Medizin
Professur: M - Keiner Professur zugeordnet
Sammlung:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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