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Titel: Can magnetic resonance imaging replace conventional computerized tomography for follow-up of patients with testicular cancer? A systematic review
VerfasserIn: Busch, Jonas
Schmidt, Stefanie
Albers, Peter
Heinzelbecker, Julia UdsID
Kliesch, Sabine
Lackner, Julia
Pfister, David
Ruf, Christian
Winter, Christian
Zengerling, Friedemann
Beyersdorff, Dirk
Sprache: Englisch
In:
Titel: World Journal of Urology
Verlag/Plattform: Springer Nature
Erscheinungsjahr: 2022
Freie Schlagwörter: Testicular cancer
Follow-up care
Computerized tomography imaging
Magnetic resonance imaging
Recurrence
Metastasis
DDC-Sachgruppe: 610 Medizin, Gesundheit
Dokumenttyp: Journalartikel / Zeitschriftenartikel
Abstract: Purpose Follow-up protocols for patients with testicular cancer (TC) have significantly reduced the number of cross-sectional imaging studies to reduce radiation exposure. At present, it is unclear whether magnetic resonance imaging (MRI) could replace conventional computerized tomography (CT) imaging. The objective of this study is to summarize the scientific evidence on this topic and to review guideline recommendations with regard to the use of MRI. Methods A systematic literature review was performed searching Medline and Cochrane databases for prospective studies on patients with TC in the follow-up care (last search in February 2021). Additionally, guideline recommendations for TC were screened. Data extraction and quality assessment of included studies were performed and used for a descriptive presentation of results. Results A total of four studies including two ongoing trials were identified. Overall, the scientific evidence of prospective comparative studies is based on 102 patients. Data suggest that abdominal imaging with MRI can replace conventional CT for detection of lymph node metastasis of the retroperitoneum to spare radiation exposure and contrast media application. However, experienced radiologists are needed. Clinical guidelines are aware of the risk of diagnosis-induced secondary malignancy due to CT imaging and some have adapted their recommendations accordingly. Results of the two ongoing trials on 738 patients are expected soon to provide more reliable results on this topic. Conclusions There is growing evidence that abdominopelvic MRI imaging can replace CT imaging during follow-up of patients with TC in order to reduce radiation exposure and diagnosis-induced secondary malignancy.
DOI der Erstveröffentlichung: 10.1007/s00345-022-03931-6
URL der Erstveröffentlichung: https://link.springer.com/article/10.1007/s00345-022-03931-6
Link zu diesem Datensatz: urn:nbn:de:bsz:291--ds-376995
hdl:20.500.11880/34103
http://dx.doi.org/10.22028/D291-37699
ISSN: 1433-8726
0724-4983
Datum des Eintrags: 25-Okt-2022
Fakultät: M - Medizinische Fakultät
Fachrichtung: M - Urologie und Kinderurologie
Professur: M - Prof. Dr. Michael Stöckle
Sammlung:SciDok - Der Wissenschaftsserver der Universität des Saarlandes



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