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doi:10.22028/D291-37692
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Titel: | Preoperative clinical and radiographic predictors of major vascular surgery in patients with testicular cancer undergoing post-chemotherapy residual tumor resection (PC-RPLND) |
VerfasserIn: | Nini, Alessandro ![]() Boschheidgen, Matthias Hiester, Andreas Winter, Christian Antoch, Gerald Schimmöller, Lars Albers, Peter |
Sprache: | Englisch |
In: | |
Titel: | World Journal of Urology |
Bandnummer: | 40 (2022) |
Heft: | 2 |
Seiten: | 349-354 |
Verlag/Plattform: | Springer Nature |
Erscheinungsjahr: | 2021 |
Freie Schlagwörter: | Testicular cancer PC-RPLND Radiology Vascular surgery |
DDC-Sachgruppe: | 610 Medizin, Gesundheit |
Dokumenttyp: | Journalartikel / Zeitschriftenartikel |
Abstract: | Purpose To evaluate the probability to correctly predict major vascular surgery (MVS) in patients undergoing postchemotherapy retroperitoneal lymph node dissection (PC-RPLND) for testicular cancer. Methods From a database of 504 RPLNDs performed in 434 patients (2008–2018), 78 patients submitted to PC-RPLND for non-seminoma germ-cell cancer after cisplatin-based chemotherapy with available preoperative CT scans were identifed. Second PC-PLNDs (Re-Dos), salvage RPLNDs, or RPLNDs for late-relapse were excluded as well as thoraco-abdominal approaches. Preoperative imaging was reviewed by a urologist and a radiologist blinded to operative details. Results Of 78 patients, 16 (20.5%) underwent MVS (caval and/or aortic replacement or reconstruction). On univariable analyses, transversal diameter, sagittal diameter, tumor volume, aorta- and cava-tumor contact angle, poor IGCCCG score, clinical stage III and preoperative positive markers were predictors of MVS (all p values≤0.01). At multivariable analyses aorta- (cut-of 64°) and cava-tumor contact angle (cut-of 98°) and poor IGCCCG score represented the three most important predictors of MVS (all p values≤0.05). The model constructed has a PPV 100%, NPV 87% and an accuracy of 88%. Conclusions Presence of aorta-tumor contact angle≥64°, cava-tumor contact angle≥98° and poor IGCCCG score identify correctly 9 out of 10 patients requiring MVS at the time of frst PC-RPLND. |
DOI der Erstveröffentlichung: | 10.1007/s00345-021-03870-8 |
URL der Erstveröffentlichung: | https://link.springer.com/article/10.1007/s00345-021-03870-8 |
Link zu diesem Datensatz: | urn:nbn:de:bsz:291--ds-376928 hdl:20.500.11880/34097 http://dx.doi.org/10.22028/D291-37692 |
ISSN: | 1433-8726 0724-4983 |
Datum des Eintrags: | 25-Okt-2022 |
Fakultät: | M - Medizinische Fakultät |
Fachrichtung: | M - Urologie und Kinderurologie |
Professur: | M - Prof. Dr. Michael Stöckle |
Sammlung: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
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