Please use this identifier to cite or link to this item:
Volltext verfügbar? / Dokumentlieferung
doi:10.22028/D291-37692
Title: | Preoperative clinical and radiographic predictors of major vascular surgery in patients with testicular cancer undergoing post-chemotherapy residual tumor resection (PC-RPLND) |
Author(s): | Nini, Alessandro Boschheidgen, Matthias Hiester, Andreas Winter, Christian Antoch, Gerald Schimmöller, Lars Albers, Peter |
Language: | English |
Title: | World Journal of Urology |
Volume: | 40 (2022) |
Issue: | 2 |
Pages: | 349-354 |
Publisher/Platform: | Springer Nature |
Year of Publication: | 2021 |
Free key words: | Testicular cancer PC-RPLND Radiology Vascular surgery |
DDC notations: | 610 Medicine and health |
Publikation type: | Journal Article |
Abstract: | Purpose To evaluate the probability to correctly predict major vascular surgery (MVS) in patients undergoing postchemotherapy retroperitoneal lymph node dissection (PC-RPLND) for testicular cancer. Methods From a database of 504 RPLNDs performed in 434 patients (2008–2018), 78 patients submitted to PC-RPLND for non-seminoma germ-cell cancer after cisplatin-based chemotherapy with available preoperative CT scans were identifed. Second PC-PLNDs (Re-Dos), salvage RPLNDs, or RPLNDs for late-relapse were excluded as well as thoraco-abdominal approaches. Preoperative imaging was reviewed by a urologist and a radiologist blinded to operative details. Results Of 78 patients, 16 (20.5%) underwent MVS (caval and/or aortic replacement or reconstruction). On univariable analyses, transversal diameter, sagittal diameter, tumor volume, aorta- and cava-tumor contact angle, poor IGCCCG score, clinical stage III and preoperative positive markers were predictors of MVS (all p values≤0.01). At multivariable analyses aorta- (cut-of 64°) and cava-tumor contact angle (cut-of 98°) and poor IGCCCG score represented the three most important predictors of MVS (all p values≤0.05). The model constructed has a PPV 100%, NPV 87% and an accuracy of 88%. Conclusions Presence of aorta-tumor contact angle≥64°, cava-tumor contact angle≥98° and poor IGCCCG score identify correctly 9 out of 10 patients requiring MVS at the time of frst PC-RPLND. |
DOI of the first publication: | 10.1007/s00345-021-03870-8 |
URL of the first publication: | https://link.springer.com/article/10.1007/s00345-021-03870-8 |
Link to this record: | urn:nbn:de:bsz:291--ds-376928 hdl:20.500.11880/34097 http://dx.doi.org/10.22028/D291-37692 |
ISSN: | 1433-8726 0724-4983 |
Date of registration: | 25-Oct-2022 |
Faculty: | M - Medizinische Fakultät |
Department: | M - Urologie und Kinderurologie |
Professorship: | M - Prof. Dr. Michael Stöckle |
Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
Files for this record:
There are no files associated with this item.
Items in SciDok are protected by copyright, with all rights reserved, unless otherwise indicated.