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Titel: The Accuracy of Cytology, Colposcopy and Pathology in Evaluating Precancerous Cervical Lesions
VerfasserIn: Pleş, Liana
Radosa, Julia-Carolina
Sima, Romina-Marina
Chicea, Radu
Olaru, Octavian-Gabriel
Poenaru, Mircea-Octavian
Sprache: Englisch
Titel: Diagnostics
Bandnummer: 12
Heft: 8
Verlag/Plattform: MDPI
Erscheinungsjahr: 2022
Freie Schlagwörter: colposcopy
cervical cancer
screening
biopsy
accuracy
audit
DDC-Sachgruppe: 610 Medizin, Gesundheit
Dokumenttyp: Journalartikel / Zeitschriftenartikel
Abstract: Cervical cancer (CC) is the third most common cancer in the world, and Romania has the highest incidence of cervical cancer in Europe. The aim of this study was to evaluate the correlation between cytology, colposcopy, and pathology for the early detection of premalignant cervical lesions in a group of Romanian patients. Methods: This observational type 2 cohort study included 128 women from our unit, “Bucur” Maternity, who were referred for cervical cancer screening. Age, clinical diagnosis, cytology results, colposcopy impression, and biopsy results were considered. Colposcopy was performed by two experienced examiners. The pathological examination was performed by an experienced pathologist. Results: The cytology found high-grade squamous intraepithelial lesions in 60.9% of patients, low-grade squamous intraepithelial lesions in 28.1%, atypical squamous cells for which a high-grade lesion could not be excluded in 9.4%, and atypical squamous cells of undetermined significance, known as repeated LSIL, in 1.6%. The first evaluator identified low-grade lesions in 56.3%, high-grade lesions in 40.6%, and invasion in 3.1% of patients. The second evaluator identified low-grade lesions in 59.4%, high-grade lesions in 32.0%, and invasion in 8.6% of patients. The pathological exam identified low-grade lesions in 64.1%, high-grade lesions in 25%, and carcinoma in 14% of patients. The colposcopic accuracy was greater than the cytologic accuracy. Conclusions: Colposcopy remains an essential tool for the identification of cervical premalignant cancer cells. Standardization of the protocol provided an insignificant interobserver variability and can serve as support for further postgraduate teaching.
DOI der Erstveröffentlichung: 10.3390/diagnostics12081947
Link zu diesem Datensatz: urn:nbn:de:bsz:291--ds-370863
hdl:20.500.11880/33668
http://dx.doi.org/10.22028/D291-37086
ISSN: 2075-4418
Datum des Eintrags: 26-Aug-2022
Fakultät: M - Medizinische Fakultät
Fachrichtung: M - Frauenheilkunde
Professur: M - Keiner Professur zugeordnet
Sammlung:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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