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Titel: Postpartum Assessment of the Correlation between Serum Hormone Levels of Estradiol, Progesterone, Prolactin and ß-HCG and Blood Pressure Measurements in Pre-Eclampsia Patients
VerfasserIn: Kasoha, Mariz
Takacs, Zoltan
Dumé, Jacob
Findeklee, Sebastian
Gerlinger, Christoph
Sima, Romina-Marina
Ples, Liana
Solomayer, Erich-Franz
Haj Hamoud, Bashar
Sprache: Englisch
Titel: Diagnostics
Bandnummer: 12
Heft: 7
Verlag/Plattform: MDPI
Erscheinungsjahr: 2022
Freie Schlagwörter: preeclampsia
hypertension
hormones
postpartum
serum
DDC-Sachgruppe: 610 Medizin, Gesundheit
Dokumenttyp: Journalartikel / Zeitschriftenartikel
Abstract: Background: Preeclampsia is a pregnancy-related hypertensive disease. Aberrant hormone levels have been implicated in blood pressure disorders. This study investigated the association of postpartum maternal serum hormone levels of estradiol, progesterone, prolactin, and ß-HCG with poorer PE-related complications including arterial hypertension. Methods: Thirty patient women with preeclampsia, and twenty women with uncomplicated pregnancy were included in this study. Serum levels of estradiol, progesterone, prolactin, and ß-HCG were determined immediately after delivery, and on the first and third postpartum days by means of ECLIA. Results: Compared with normal pregnancy cases, preeclampsia cases had higher serum levels of ß-HCG levels on Day 0 (319%), of progesterone on Day-0 (207%) and Day-1 (178%), and of estradiol on Day-1 (187%) and Day-3 (185%). Increased prolactin levels were positively associated with disease severity and estradiol and progesterone levels were decreased in poorer preeclampsia features including disease onset and IUGR diagnosis. No significant correlation between different hormone levels and blood pressure measurements was reported. Conclusions: This study is the first that detected postpartum maternal serum hormone levels and their correlation with blood pressure measurements in preeclampsia. We believe that the persistent arterial hypertension in the puerperium in preeclampsia as well as poorer disease specifications are most likely not of hormonal origin. Larger, well-defined prospective studies are recommended.
DOI der Erstveröffentlichung: 10.3390/diagnostics12071700
Link zu diesem Datensatz: urn:nbn:de:bsz:291--ds-368964
hdl:20.500.11880/33586
http://dx.doi.org/10.22028/D291-36896
ISSN: 2075-4418
Datum des Eintrags: 8-Aug-2022
Fakultät: M - Medizinische Fakultät
Fachrichtung: M - Frauenheilkunde
Professur: M - Prof. Dr. E.-F. Solomayer
Sammlung:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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