Bitte benutzen Sie diese Referenz, um auf diese Ressource zu verweisen:
doi:10.22028/D291-36896
Titel: | Postpartum Assessment of the Correlation between Serum Hormone Levels of Estradiol, Progesterone, Prolactin and ß-HCG and Blood Pressure Measurements in Pre-Eclampsia Patients |
VerfasserIn: | Kasoha, Mariz Takacs, Zoltan Dumé, Jacob Findeklee, Sebastian Gerlinger, Christoph Sima, Romina-Marina Ples, Liana Solomayer, Erich-Franz Haj Hamoud, Bashar |
Sprache: | Englisch |
Titel: | Diagnostics |
Bandnummer: | 12 |
Heft: | 7 |
Verlag/Plattform: | MDPI |
Erscheinungsjahr: | 2022 |
Freie Schlagwörter: | preeclampsia hypertension hormones postpartum serum |
DDC-Sachgruppe: | 610 Medizin, Gesundheit |
Dokumenttyp: | Journalartikel / Zeitschriftenartikel |
Abstract: | Background: Preeclampsia is a pregnancy-related hypertensive disease. Aberrant hormone levels have been implicated in blood pressure disorders. This study investigated the association of postpartum maternal serum hormone levels of estradiol, progesterone, prolactin, and ß-HCG with poorer PE-related complications including arterial hypertension. Methods: Thirty patient women with preeclampsia, and twenty women with uncomplicated pregnancy were included in this study. Serum levels of estradiol, progesterone, prolactin, and ß-HCG were determined immediately after delivery, and on the first and third postpartum days by means of ECLIA. Results: Compared with normal pregnancy cases, preeclampsia cases had higher serum levels of ß-HCG levels on Day 0 (319%), of progesterone on Day-0 (207%) and Day-1 (178%), and of estradiol on Day-1 (187%) and Day-3 (185%). Increased prolactin levels were positively associated with disease severity and estradiol and progesterone levels were decreased in poorer preeclampsia features including disease onset and IUGR diagnosis. No significant correlation between different hormone levels and blood pressure measurements was reported. Conclusions: This study is the first that detected postpartum maternal serum hormone levels and their correlation with blood pressure measurements in preeclampsia. We believe that the persistent arterial hypertension in the puerperium in preeclampsia as well as poorer disease specifications are most likely not of hormonal origin. Larger, well-defined prospective studies are recommended. |
DOI der Erstveröffentlichung: | 10.3390/diagnostics12071700 |
Link zu diesem Datensatz: | urn:nbn:de:bsz:291--ds-368964 hdl:20.500.11880/33586 http://dx.doi.org/10.22028/D291-36896 |
ISSN: | 2075-4418 |
Datum des Eintrags: | 8-Aug-2022 |
Fakultät: | M - Medizinische Fakultät |
Fachrichtung: | M - Frauenheilkunde |
Professur: | M - Prof. Dr. E.-F. Solomayer |
Sammlung: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
Dateien zu diesem Datensatz:
Datei | Beschreibung | Größe | Format | |
---|---|---|---|---|
diagnostics-12-01700-v2.pdf | 2,06 MB | Adobe PDF | Öffnen/Anzeigen |
Diese Ressource wurde unter folgender Copyright-Bestimmung veröffentlicht: Lizenz von Creative Commons