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Titel: High probability of comorbidities in bronchial asthma in Germany
VerfasserIn: Heck, S.
Al-Shobash, S.
Rapp, D.
Le, D. D.
Omlor, A.
Bekhit, A.
Flaig, M.
Al-Kadah, B.
Herian, W.
Bals, R.
Wagenpfeil, S.
Dinh, Q. T.
Sprache: Englisch
Titel: npj Primary Care Respiratory Medicine
Bandnummer: 27
Heft: 1
Verlag/Plattform: Springer Nature
Erscheinungsjahr: 2017
Freie Schlagwörter: Diseases
Epidemiology
DDC-Sachgruppe: 610 Medizin, Gesundheit
Dokumenttyp: Journalartikel / Zeitschriftenartikel
Abstract: Clinical experience has shown that allergic and non-allergic respiratory, metabolic, mental, and cardiovascular disorders sometimes coexist with bronchial asthma. However, no study has been carried out that calculates the chance of manifestation of these disorders with bronchial asthma in Saarland and Rhineland-Palatinate, Germany. Using ICD10 diagnoses from health care institutions, the present study systematically analyzed the co-prevalence and odds ratios of comorbidities in the asthma population in Germany. The odds ratios were adjusted for age and sex for all comorbidities for patients with asthma vs. without asthma. Bronchial asthma was strongly associated with allergic and with a lesser extent to non-allergic comorbidities: OR 7.02 (95% CI:6.83–7.22) for allergic rhinitis; OR 4.98 (95%CI:4.67–5.32) allergic conjunctivitis; OR 2.41 (95%CI:2.33–2.52) atopic dermatitis; OR 2.47 (95%CI:2.16–2.82) food allergy, and OR 1.69 (95%CI:1.61–1.78) drug allergy. Interestingly, increased ORs were found for respiratory diseases: 2.06 (95%CI:1.64–2.58) vocal dysfunction; 1.83 (95%CI:1.74–1.92) pneumonia; 1.78 (95%CI:1.73–1.84) sinusitis; 1.71 (95%CI:1.65–1.78) rhinopharyngitis; 2.55 (95%CI:2.03–3.19) obstructive sleep apnea; 1.42 (95%CI:1.25–1.61) pulmonary embolism, and 3.75 (95%CI:1.64–8.53) bronchopulmonary aspergillosis. Asthmatics also suffer from psychiatric, metabolic, cardiac or other comorbidities. Myocardial infarction (OR 0.86, 95%CI:0.79–0.94) did not coexist with asthma. Based on the calculated chances of manifestation for these comorbidities, especially allergic and respiratory, to a lesser extent also metabolic, cardiovascular, and mental disorders should be taken into consideration in the diagnostic and treatment strategy of bronchial asthma.
DOI der Erstveröffentlichung: 10.1038/s41533-017-0026-x
URL der Erstveröffentlichung: https://www.nature.com/articles/s41533-017-0026-x
Link zu diesem Datensatz: urn:nbn:de:bsz:291--ds-366919
hdl:20.500.11880/33334
http://dx.doi.org/10.22028/D291-36691
ISSN: 2055-1010
Datum des Eintrags: 7-Jul-2022
Fakultät: M - Medizinische Fakultät
Fachrichtung: M - Hals-Nasen-Ohrenheilkunde
M - Innere Medizin
M - Medizinische Biometrie, Epidemiologie und medizinische Informatik
Professur: M - Prof. Dr. Robert Bals
M - Prof. Dr. Stefan Wagenpfeil
M - Keiner Professur zugeordnet
Sammlung:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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