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doi:10.22028/D291-36691
Titel: | High probability of comorbidities in bronchial asthma in Germany |
VerfasserIn: | Heck, S. Al-Shobash, S. Rapp, D. Le, D. D. Omlor, A. Bekhit, A. Flaig, M. Al-Kadah, B. Herian, W. Bals, R. Wagenpfeil, S. Dinh, Q. T. |
Sprache: | Englisch |
Titel: | npj Primary Care Respiratory Medicine |
Bandnummer: | 27 |
Heft: | 1 |
Verlag/Plattform: | Springer Nature |
Erscheinungsjahr: | 2017 |
Freie Schlagwörter: | Diseases Epidemiology |
DDC-Sachgruppe: | 610 Medizin, Gesundheit |
Dokumenttyp: | Journalartikel / Zeitschriftenartikel |
Abstract: | Clinical experience has shown that allergic and non-allergic respiratory, metabolic, mental, and cardiovascular disorders sometimes coexist with bronchial asthma. However, no study has been carried out that calculates the chance of manifestation of these disorders with bronchial asthma in Saarland and Rhineland-Palatinate, Germany. Using ICD10 diagnoses from health care institutions, the present study systematically analyzed the co-prevalence and odds ratios of comorbidities in the asthma population in Germany. The odds ratios were adjusted for age and sex for all comorbidities for patients with asthma vs. without asthma. Bronchial asthma was strongly associated with allergic and with a lesser extent to non-allergic comorbidities: OR 7.02 (95% CI:6.83–7.22) for allergic rhinitis; OR 4.98 (95%CI:4.67–5.32) allergic conjunctivitis; OR 2.41 (95%CI:2.33–2.52) atopic dermatitis; OR 2.47 (95%CI:2.16–2.82) food allergy, and OR 1.69 (95%CI:1.61–1.78) drug allergy. Interestingly, increased ORs were found for respiratory diseases: 2.06 (95%CI:1.64–2.58) vocal dysfunction; 1.83 (95%CI:1.74–1.92) pneumonia; 1.78 (95%CI:1.73–1.84) sinusitis; 1.71 (95%CI:1.65–1.78) rhinopharyngitis; 2.55 (95%CI:2.03–3.19) obstructive sleep apnea; 1.42 (95%CI:1.25–1.61) pulmonary embolism, and 3.75 (95%CI:1.64–8.53) bronchopulmonary aspergillosis. Asthmatics also suffer from psychiatric, metabolic, cardiac or other comorbidities. Myocardial infarction (OR 0.86, 95%CI:0.79–0.94) did not coexist with asthma. Based on the calculated chances of manifestation for these comorbidities, especially allergic and respiratory, to a lesser extent also metabolic, cardiovascular, and mental disorders should be taken into consideration in the diagnostic and treatment strategy of bronchial asthma. |
DOI der Erstveröffentlichung: | 10.1038/s41533-017-0026-x |
URL der Erstveröffentlichung: | https://www.nature.com/articles/s41533-017-0026-x |
Link zu diesem Datensatz: | urn:nbn:de:bsz:291--ds-366919 hdl:20.500.11880/33334 http://dx.doi.org/10.22028/D291-36691 |
ISSN: | 2055-1010 |
Datum des Eintrags: | 7-Jul-2022 |
Fakultät: | M - Medizinische Fakultät |
Fachrichtung: | M - Hals-Nasen-Ohrenheilkunde M - Innere Medizin M - Medizinische Biometrie, Epidemiologie und medizinische Informatik |
Professur: | M - Prof. Dr. Robert Bals M - Prof. Dr. Stefan Wagenpfeil M - Keiner Professur zugeordnet |
Sammlung: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
Dateien zu diesem Datensatz:
Datei | Beschreibung | Größe | Format | |
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s41533-017-0026-x.pdf | 906 kB | Adobe PDF | Öffnen/Anzeigen |
Diese Ressource wurde unter folgender Copyright-Bestimmung veröffentlicht: Lizenz von Creative Commons