Please use this identifier to cite or link to this item: doi:10.22028/D291-36543
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Title: Percutaneous Mechanical Circulation Support Combined with Extracorporeal Membrane Oxygenation (oxyRVAD) in Secondary Right Heart Failure
Author(s): Lepper, Philipp M.
Hörsch, Sabrina I.
Seiler, Frederik
Kamp, Annegret
Becker, Sören L.
Lensch, Christian
Conzelmann, Lars O.
Haake, Hendrik
Muellenbach, Ralf M.
Bals, Robert
Kredel, Markus
Langer, Frank
Wilkens, Heinrike
Trudzinski, Franziska C.
Language: English
Title: ASAIO Journal
Volume: 64
Issue: 4
Pages: e64-e67
Publisher/Platform: Lippincott Williams & Wilkins
Year of Publication: 2018
Free key words: mechanical circulation support
RVAD
ECMO
pulmonary embolism
CTEPH
DDC notations: 610 Medicine and health
Publikation type: Journal Article
Abstract: Right heart failure (RHF) because of pulmonary hypertension (PH) is a frequently encountered clinical problem with high mortality. The last resort, if pharmacological therapy fails, is mechanical circulatory support. There is a lack of percutaneous systems to support the right ventricle (RV). Venoarterial extracorporeal membrane oxygenation is widely used as a bailout in acute RHF in non-left ventricular assist device patients. Venoarterial extracorporeal membrane oxygenation does not unload the left ventricle and may cause failure of the left ventricle if used for a longer period of time. We report the long-term use of an ECMO-based percutaneous right ventricular assist system (oxyRVAD) capable to deliver up to 6 L/min of blood flow with a returning cannula placed in the main pulmonary artery used in RHF originating from PH with poor oxygenation. We present a series of four patients on oxyRVAD (mean treatment duration 15 ± 7.6 days). Patients benefited from the system clinically; however, two patients eventually died while on oxyRVAD. Nevertheless, we provide a proof-of-concept of this system in PH patients, which is feasible and might provide a useful “bridge-to-recovery” or “bridge-to-transplant” option in the management of patients with severe RHF because of PH.
DOI of the first publication: 10.1097/MAT.0000000000000754
URL of the first publication: https://journals.lww.com/asaiojournal/Fulltext/2018/07000/Percutaneous_Mechanical_Circulation_Support.26.aspx
Link to this record: urn:nbn:de:bsz:291--ds-365436
hdl:20.500.11880/33195
http://dx.doi.org/10.22028/D291-36543
ISSN: 1058-2916
Date of registration: 22-Jun-2022
Faculty: M - Medizinische Fakultät
Department: M - Chirurgie
M - Infektionsmedizin
M - Innere Medizin
Professorship: M - Prof. Dr. Robert Bals
M - Prof. Dr. Sören Becker
M - Keiner Professur zugeordnet
Collections:Die Universitätsbibliographie

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