Please use this identifier to cite or link to this item: doi:10.22028/D291-36303
Volltext verfügbar? / Dokumentlieferung
Title: Device-related risk of atrial fibrillation after closure of patent foramen ovale: a systematic review and meta-analysis
Author(s): Vukadinović, Davor
Scheller, Bruno
Ukena, Christian
Ewen, Sebastian
Mahfoud, Felix
Böhm, Michael
Language: English
Title: Clinical Research in Cardiology
Volume: 111
Issue: 5
Pages: 583–587
Publisher/Platform: Springer Nature
Year of Publication: 2021
Publikation type: Journal Article
Abstract: Background Atrial fbrillation (AF) represents a frequent complication in patients after interventional closure of patent foramen ovale (PFO). We aimed to compare the incident rate and risk of AF between Amplatzer PFO and GORE (Helex and CARDIOFORM Septal Occluder) device by analyzing the data from randomized trials. Methods We included all randomized studies which reported the rate of AF after PFO closure using Amplatzer or GORE occluder in patients sufering cryptogenic stroke and compared the risk of AF between the two devices. PubMed and Cochrane library were searched for eligible studies published until July 2020. Results Rate of all cases of incident AF from randomized trials with Amplatzer in the interventional group was 3.93% (30/763) vs. 1.46% (11/751) in the respective medical group (RR of 2.57, 95% CI 1.31–5.03, p=0.006). The incidence of incident AF from randomized trial with GORE device was 6.57% (29/441) vs. 0.44% (1/223) in the respective medical group (RR of 14.66, 95% CI 2.01–106.95, p=0.008). The p for interaction between the two devices regarding risk of AF was 0.10. Conclusions The results suggest lower risk expressed by lower rate of incident AF after PFO closure using Amplatzer PFO Occluder when compared with GORE Occluder. However, these fndings are derived from secondary analyses and should be scrutinized using appropriate screening tool for AF following PFO closure in adequately powered randomized clinical trial with a head-to-head design that compares the two devices.
DOI of the first publication: 10.1007/s00392-021-01964-2
URL of the first publication: https://link.springer.com/article/10.1007/s00392-021-01964-2
Link to this record: hdl:20.500.11880/32975
http://dx.doi.org/10.22028/D291-36303
ISSN: 1861-0692
1861-0684
Date of registration: 31-May-2022
Faculty: M - Medizinische Fakultät
Department: M - Innere Medizin
Professorship: M - Prof. Dr. Michael Böhm
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

Files for this record:
There are no files associated with this item.


Items in SciDok are protected by copyright, with all rights reserved, unless otherwise indicated.