Please use this identifier to cite or link to this item: doi:10.22028/D291-36031
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Title: Coronavirus Disease 2019 (COVID-19) and its implications for cardiovascular care: expert document from the German Cardiac Society and the World Heart Federation
Author(s): Böhm, Michael
Frey, Norbert
Giannitsis, Evangelos
Sliwa, Karen
Zeiher, Andreas M.
Language: English
Title: Clinical Research in Cardiology
Volume: 109
Issue: 12
Pages: 1446–1459
Publisher/Platform: Springer Nature
Year of Publication: 2020
Publikation type: Journal Article
Abstract: Coronavirus diseases 2019 (COVID-19) has become a worldwide pandemic afecting people at high risk and particularly at advanced age, cardiovascular and pulmonary disease. As cardiovascular patients are at high risk but also have dyspnea and fatigue as leading symptoms, prevention, diagnostics and treatment in these patients are important to provide adequate care for those with or without COVID-19 but most importantly when comorbid cardiovascular conditions are present. Severe COVID-19 with acute respiratory distress (ARDS) is challenging as patients with elevated myocardial markers such as troponin are at enhanced high risk for fatal outcomes. As angiotensin-converting enzyme 2 (ACE2) is regarded as the viral receptor for cell entry and as the Coronavirus is downregulating this enzyme, which provides cardiovascular and pulmonary protection, there is ongoing discussions on whether treatment with cardiovascular drugs, which upregulate the viral receptor ACE2 should be modifed. As most of the COVID-19 patients have cardiovascular comorbidities like hypertension, diabetes, coronary artery disease and heart failure, which imposes a high risk on these patients, cardiovascular therapy should not be modifed or even withdrawn. As cardiac injury is a common feature of COVID-19 associated ARDS and is linked with poor outcomes, swift diagnostic management and specialist care of cardiovascular patients in the area of COVID-19 is of particular importance and deserves special attention.
DOI of the first publication: 10.1007/s00392-020-01656-3
URL of the first publication: https://link.springer.com/article/10.1007/s00392-020-01656-3
Link to this record: hdl:20.500.11880/32827
http://dx.doi.org/10.22028/D291-36031
ISSN: 1861-0692
1861-0684
Date of registration: 21-Apr-2022
Faculty: M - Medizinische Fakultät
Department: M - Innere Medizin
Professorship: M - Prof. Dr. Michael Böhm
Collections:Die Universitätsbibliographie

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