Please use this identifier to cite or link to this item: doi:10.22028/D291-35053
Title: New Kendomycin Derivative Isolated from Streptomyces sp. Cl 58-27
Author(s): Paulus, Constanze
Gromyko, Oleksandr
Luzhetskyy, Andriy
Language: English
Title: Molecules
Volume: 26
Issue: 22
Publisher/Platform: MDPI
Year of Publication: 2021
Free key words: polyketide synthases
DDC notations: 500 Science
Publikation type: Journal Article
Abstract: In the course of screening new streptomycete strains, the strain Streptomyces sp. Cl 58-27 caught our attention due to its interesting secondary metabolite production profile. Here, we report the isolation and characterization of an ansamycin natural product that belongs structurally to the already known kendomycins. The structure of the new kendomycin E was elucidated using NMR spectroscopy, and the corresponding biosynthetic gene cluster was identified by sequencing the genome of Streptomyces sp. Cl 58-27 and conducting a detailed analysis of secondary metabolism gene clusters using bioinformatic tools.
DOI of the first publication: 10.3390/molecules26226834
Link to this record: urn:nbn:de:bsz:291--ds-350538
ISSN: 1420-3049
Date of registration: 6-Jan-2022
Description of the related object: Supplementary Material
Related object:
Faculty: NT - Naturwissenschaftlich- Technische Fakultät
Department: NT - Pharmazie
Professorship: NT - Prof. Dr. Andriy Luzhetskyy
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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