Bitte benutzen Sie diese Referenz, um auf diese Ressource zu verweisen: doi:10.22028/D291-34249
Titel: Emerging Biofabrication Techniques: A Review on Natural Polymers for Biomedical Applications
VerfasserIn: Puertas-Bartolomé, María
Mora-Boza, Ana
García-Fernández, Luis
Sprache: Englisch
Titel: Polymers
Bandnummer: 13
Heft: 8
Verlag/Plattform: MDPI
Erscheinungsjahr: 2021
Freie Schlagwörter: biofabrication
microfluidics
electrospinning
3D printing
electrospraying
natural polymers
cell encapsulation
DDC-Sachgruppe: 570 Biowissenschaften, Biologie
Dokumenttyp: Journalartikel / Zeitschriftenartikel
Abstract: Natural polymers have been widely used for biomedical applications in recent decades. They offer the advantages of resembling the extracellular matrix of native tissues and retaining biochemical cues and properties necessary to enhance their biocompatibility, so they usually improve the cellular attachment and behavior and avoid immunological reactions. Moreover, they offer a rapid degradability through natural enzymatic or chemical processes. However, natural polymers present poor mechanical strength, which frequently makes the manipulation processes difficult. Recent advances in biofabrication, 3D printing, microfluidics, and cell-electrospinning allow the manufacturing of complex natural polymer matrixes with biophysical and structural properties similar to those of the extracellular matrix. In addition, these techniques offer the possibility of incorporating different cell lines into the fabrication process, a revolutionary strategy broadly explored in recent years to produce cell-laden scaffolds that can better mimic the properties of functional tissues. In this review, the use of 3D printing, microfluidics, and electrospinning approaches has been extensively investigated for the biofabrication of naturally derived polymer scaffolds with encapsulated cells intended for biomedical applications (e.g., cell therapies, bone and dental grafts, cardiovascular or musculoskeletal tissue regeneration, and wound healing).
DOI der Erstveröffentlichung: 10.3390/polym13081209
Link zu diesem Datensatz: urn:nbn:de:bsz:291--ds-342493
hdl:20.500.11880/31428
http://dx.doi.org/10.22028/D291-34249
ISSN: 2073-4360
Datum des Eintrags: 24-Jun-2021
Fakultät: NT - Naturwissenschaftlich- Technische Fakultät
Fachrichtung: NT - Biowissenschaften
Professur: NT - Keiner Professur zugeordnet
Sammlung:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

Dateien zu diesem Datensatz:
Datei Beschreibung GrößeFormat 
polymers-13-01209.pdf3,6 MBAdobe PDFÖffnen/Anzeigen


Diese Ressource wurde unter folgender Copyright-Bestimmung veröffentlicht: Lizenz von Creative Commons Creative Commons