Please use this identifier to cite or link to this item: doi:10.22028/D291-33602
Title: Cyst formation in the subchondral bone following cartilage repair
Author(s): Gao, Liang
Cucchiarini, Magali
Madry, Henning
Language: English
Title: Clinical and Translational Medicine
Volume: 10
Issue: 8
Publisher/Platform: Wiley
Year of Publication: 2020
Free key words: bone cyst
cartilage repair
osteochondral unit
subchondral bone
DDC notations: 610 Medicine and health
Publikation type: Journal Article
Abstract: Subchondral bone cysts represent an early postoperative sign associated with many articular cartilage repair procedures. They may be defined as an abnormal cavity within the subchondral bone in close proximity of a treated cartilage defect with a possible communication to the joint cavity in the absence of osteoarthritis. Two synergistic mechanisms of subchondral cyst formation, the theory of internal upregulation of local proinflammatory factors, and the external hydraulic theory, are proposed to explain their occurrence. This review describes subchondral bone cysts in the context of articular cartilage repair to improve investigations of these pathological changes. It summarizes their epidemiology in both preclinical and clinical settings with a focus on individual cartilage repair procedures, examines an algorithm for subchondral bone analysis, elaborates on the underlying mechanism of subchondral cyst formation, and condenses the clinical implications and perspectives on subchondral bone cyst formation in cartilage repair.
DOI of the first publication: 10.1002/ctm2.248
Link to this record: urn:nbn:de:bsz:291--ds-336021
ISSN: 2001-1326
Date of registration: 22-Mar-2021
Faculty: M - Medizinische Fakultät
Department: M - Orthopädie
Professorship: M - Prof. Dr. Henning Madry
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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