Please use this identifier to cite or link to this item: doi:10.22028/D291-33450
Title: Nanomaterials for the Diagnosis and Treatment of Urinary Tract Infections
Author(s): Qindeel, Maimoona
Barani, Mahmood
Rahdar, Abbas
Arshad, Rabia
Cucchiarini, Magali
Language: English
Title: Nanomaterials
Volume: 11
Issue: 2
Publisher/Platform: MDPI
Year of Publication: 2021
Free key words: urinary tract infections
multidrug resistance
surface-tailored nanomedicines
DDC notations: 610 Medicine and health
Publikation type: Journal Article
Abstract: The diagnosis and treatment of urinary tract infections (UTIs) remain challenging due to the lack of convenient assessment techniques and to the resistance to conventional antimicrobial therapy, showing the need for novel approaches to address such problems. In this regard, nanotechnology has a strong potential for both the diagnosis and therapy of UTIs via controlled delivery of antimicrobials upon stable, effective and sustained drug release. On one side, nanoscience allowed the production of various nanomaterial-based evaluation tools as precise, effective, and rapid procedures for the identification of UTIs. On the other side, nanotechnology brought tremendous breakthroughs for the treatment of UTIs based on the use of metallic nanoparticles (NPs) for instance, owing to the antimicrobial properties of metals, or of surface-tailored nanocarriers, allowing to overcome multidrug-resistance and prevent biofilm formation via targeted drug delivery to desired sites of action and preventing the development of cytotoxic processes in healthy cells. The goal of the current study is therefore to present the newest developments for the diagnosis and treatment of UTIs based on nanotechnology procedures in relation to the currently available techniques.
DOI of the first publication: 10.3390/nano11020546
Link to this record: urn:nbn:de:bsz:291--ds-334502
ISSN: 2079-4991
Date of registration: 1-Mar-2021
Faculty: M - Medizinische Fakultät
Department: M - Orthopädie
Professorship: M - Prof. Dr. Henning Madry
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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