Please use this identifier to cite or link to this item: doi:10.22028/D291-33446
Title: Unleashing the Biological Potential of Fomes fomentarius via Dry and Wet Milling
Author(s): Darkal, Abdul Karim
Zuraik, Mhd Mouayad
Ney, Yannick
Nasim, Muhammad Jawad
Jacob, Claus
Language: English
Title: Antioxidants
Volume: 10
Issue: 2
Publisher/Platform: MDPI
Year of Publication: 2021
Free key words: antioxidant
ball milling
Fomes fomentarius
heat sterilization
phytochemical screening
redox sponge
DDC notations: 500 Science
Publikation type: Journal Article
Abstract: Fomes fomentarius, usually referred to as tinder conk, is a common wood-based fungus rich in many interesting phytochemicals and with an unique porous structure. Dry or wet ball milling of this sponge on a planetary mill results in small particles with sizes in the range of 10 µm or below. Suspended in water and without preservatives or other stabilizers, the resulting micro-suspensions are sterile for around six days, probably due to the increased temperatures of around 80 ◦C especially during the wet milling process. The suspensions also exhibit excellent antioxidant activities as determined in the DPPH, ferric reducing antioxidant potential (FRAP) and 2,20 -azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) assays. In the DPPH assay, IC50 values of 0.02–0.04% w/v and 0.04% w/v were observed for dry and wet milled samples, respectively. In the FRAP assay, IC50 values of <0.02% w/v and 0.04% w/v were observed for dry and wet milled samples, respectively. In contrast, the ABTS assay provided IC50 values of 0.04% w/v and 0.005% w/v, respectively. Notably, this activity is mostly—albeit not exclusively—associated with the highly porous particles and their large surfaces, although some active ingredients also diffuse into the surrounding aqueous medium. Such suspensions of natural particles carrying otherwise insoluble antioxidants on their surfaces provide an interesting avenue to unleash the antioxidant potential of materials such as sponges and barks. As dry milling also enables longer storage and transport, applications in the fields of medicine, nutrition, agriculture, materials and cosmetics are feasible.
DOI of the first publication: 10.3390/antiox10020303
Link to this record: urn:nbn:de:bsz:291--ds-334466
ISSN: 2076-3921
Date of registration: 1-Mar-2021
Description of the related object: Supplementary Materials
Related object:
Faculty: NT - Naturwissenschaftlich- Technische Fakultät
Department: NT - Pharmazie
Professorship: NT - Prof. Dr. Claus Jacob
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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