Please use this identifier to cite or link to this item: doi:10.22028/D291-32380
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Title: Liquid phase electron microscopy of biological specimens
Author(s): Peckys, Diana B.
Macías-Sánchez, Elena
de Jonge, Niels
Language: English
Title: MRS bulletin
Volume: 45
Issue: 9
Startpage: 754
Endpage: 760
Publisher/Platform: Cambridge University Press
Year of Publication: 2020
Publikation type: Journal Article
Abstract: Liquid phase electron microscopy is a new analytical method that has opened up a rapidly emerging field of research during the past decade. This article discusses this new microscopy modality within the context of imaging eukaryotic cells, bacteria, proteins, viruses, and biomineralization processes. The obtained resolution is typically not a function of the instrument, rather it is limited by the available electron dose within the limit of radiation damage. Therefore, different types of samples are best imaged with different electron microscopy (EM) modalities. The obtained information differs from that acquired with conventional EM as well as cryo-electron microscopy. This article gives an overview of achievements thus far in this area and the unique information that has been obtained. A discussion on potential future developments in the field, and technological advancements required to reach those goals conclude the article.
DOI of the first publication: 10.1557/mrs.2020.225
URL of the first publication: https://www.cambridge.org/core/journals/mrs-bulletin/article/liquid-phase-electron-microscopy-of-biological-specimens/EB532743E862836FB59660D6A674A9A4
Link to this record: hdl:20.500.11880/29750
http://dx.doi.org/10.22028/D291-32380
ISSN: 0883-7694
1938-1425
Date of registration: 28-Sep-2020
Faculty: NT - Naturwissenschaftlich- Technische Fakultät
Department: NT - Physik
Professorship: NT - Keiner Professur zugeordnet
Collections:Die Universitätsbibliographie

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