Please use this identifier to cite or link to this item: doi:10.22028/D291-28002
Title: Prevalence of Giardia intestinalis Infection in Schistosomiasis-Endemic Areas in South-Central Mali
Author(s): Fofana, Hassan K.M.
Schwarzkopf, Maren
Doumbia, Mama N.
Saye, Rénion
Nimmesgern, Anna
Landouré, Aly
Traoré, Mamadou S.
Mertens, Pascal
Utzinger, Jürg
Sacko, Moussa
Becker, Sören L.
Language: English
Title: Tropical Medicine and Infectious Disease
Volume: 4
Issue: 2
Publisher/Platform: MDPI
Year of Publication: 2019
Free key words: BD Max Enteric Parasite Panel
Giardia intestinalis
polymerase chain reaction
rapid diagnostic test
Schistosoma mansoni
stool microscopy
DDC notations: 610 Medicine and health
Publikation type: Journal Article
Abstract: Intestinal parasite infections are frequent causes of diarrhea and malnutrition among children in the tropics. Transmission of helminths and intestinal protozoa is intimately connected with conditions of poverty, including inadequate sanitation and hygiene. Concurrent infections with several intestinal pathogens may lead to excess morbidity. Yet, there is a paucity of epidemiological data from Mali. In this study, stool samples from 56 individuals, aged 2–63 years, from Bamako and Niono, south-central Mali were examined for intestinal parasites using stool microscopy. Additionally, stool samples were subjected to a rapid diagnostic test (RDT) and polymerase chain reaction (PCR) for the detection of Cryptosporidium spp. and Giardia intestinalis. The predominant pathogens were Schistosoma mansoni and G. intestinalis with prevalences of 41% and 38%, respectively. Hymenolepis nana was detected in 4% of the participants, while no eggs of soil-transmitted helminths were found. Concurrent infections with G. intestinalis and S. mansoni were diagnosed in 16% of the participants. For the detection of G. intestinalis, PCR was more sensitive (100%) than RDT (62%) and microscopy (48%). As helminth-protozoa coinfections might have important implications for morbidity control programs, future studies should employ diagnostic tools beyond stool microscopy to accurately assess the co-endemicity of giardiasis and schistosomiasis.
DOI of the first publication: 10.3390/tropicalmed4020086
Link to this record: urn:nbn:de:bsz:291--ds-280029
ISSN: 2414-6366
Date of registration: 5-Apr-2020
Faculty: M - Medizinische Fakultät
Department: M - Infektionsmedizin
Professorship: M - Prof. Dr. Dr. Sören Becker
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

Files for this record:
File Description SizeFormat 
tropicalmed-04-00086-v2.pdf251,63 kBAdobe PDFView/Open

This item is licensed under a Creative Commons License Creative Commons