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|Title:||Prevalence of Giardia intestinalis Infection in Schistosomiasis-Endemic Areas in South-Central Mali|
|Author(s):||Fofana, Hassan K.M.|
Doumbia, Mama N.
Traoré, Mamadou S.
Becker, Sören L.
|Title:||Tropical Medicine and Infectious Disease|
|Year of Publication:||2019|
|Free key words:||BD Max Enteric Parasite Panel|
polymerase chain reaction
rapid diagnostic test
|DDC notations:||610 Medicine and health|
|Publikation type:||Journal Article|
|Abstract:||Intestinal parasite infections are frequent causes of diarrhea and malnutrition among children in the tropics. Transmission of helminths and intestinal protozoa is intimately connected with conditions of poverty, including inadequate sanitation and hygiene. Concurrent infections with several intestinal pathogens may lead to excess morbidity. Yet, there is a paucity of epidemiological data from Mali. In this study, stool samples from 56 individuals, aged 2–63 years, from Bamako and Niono, south-central Mali were examined for intestinal parasites using stool microscopy. Additionally, stool samples were subjected to a rapid diagnostic test (RDT) and polymerase chain reaction (PCR) for the detection of Cryptosporidium spp. and Giardia intestinalis. The predominant pathogens were Schistosoma mansoni and G. intestinalis with prevalences of 41% and 38%, respectively. Hymenolepis nana was detected in 4% of the participants, while no eggs of soil-transmitted helminths were found. Concurrent infections with G. intestinalis and S. mansoni were diagnosed in 16% of the participants. For the detection of G. intestinalis, PCR was more sensitive (100%) than RDT (62%) and microscopy (48%). As helminth-protozoa coinfections might have important implications for morbidity control programs, future studies should employ diagnostic tools beyond stool microscopy to accurately assess the co-endemicity of giardiasis and schistosomiasis.|
|DOI of the first publication:||10.3390/tropicalmed4020086|
|Link to this record:||urn:nbn:de:bsz:291--ds-280029|
|Date of registration:||5-Apr-2020|
|Faculty:||M - Medizinische Fakultät|
|Department:||M - Infektionsmedizin|
|Professorship:||M - Prof. Dr. Dr. Sören Becker|
|Collections:||SciDok - Der Wissenschaftsserver der Universität des Saarlandes|
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