Please use this identifier to cite or link to this item: doi:10.22028/D291-27506
Title: Milling the Mistletoe: Nanotechnological Conversion of African Mistletoe (Loranthus micranthus) Intoantimicrobial Materials
Author(s): Sarfraz, Muhammad
Griffin, Sharoon
Gabour Sad, Tamara
Alhasan, Rama
Nasim, Jawad
Irfan Masood, Muhammad
Schäfer, Karl Herbert
Ejike, Chukwunonso E.C.C.
Keck, Cornelia M.
Jacob, Claus
Ebokaiwe, Azubuike P.
Language: English
Title: Antioxidants
Volume: 7
Issue: 4
Publisher/Platform: MDPI
Year of Publication: 2018
Free key words: antimicrobial activity
mistletoe nanoparticle
Loranthus micranthus
nematicidal activity
DDC notations: 540 Chemistry
Publikation type: Journal Article
Abstract: Nanosizing represents a straight forward technique to unlock the biological activity of complex plant materials. The aim of this study was to develop herbal nanoparticles with medicinal value from dried leaves and stems of Loranthus micranthus with the aid of ball-milling, high speed stirring, and high-pressure homogenization techniques. The milled nanoparticles were characterized using laser diffraction analysis, photon correlation spectroscopy analysis, and light microscopy. The average size of leaf nanoparticles was around 245 nm and that of stem nanoparticles was around 180 nm. The nanoparticles were tested for their antimicrobial and nematicidal properties against a Gram-negative bacterium Escherichia coli, a Gram-positive bacterium Staphylococcus carnosus, fungi Candida albicans and Saccharomyces cerevisiae, and a nematode Steinernemafeltiae. The results show significant activities for both leaf and (particularly) stem nanoparticles of Loranthus micranthus on all organisms tested, even at a particle concentration as low as 0.01% (w/w). The results observed indicate that nanoparticles (especially of the stem) of Loranthus micranthus could serve as novel antimicrobial agents with wide-ranging biomedical applications.
DOI of the first publication: 10.3390/antiox7040060
Link to this record: urn:nbn:de:bsz:291--ds-275066
ISSN: 2076-3921
Date of registration: 20-Feb-2020
Faculty: NT - Naturwissenschaftlich- Technische Fakultät
Department: NT - Pharmazie
Professorship: NT - Prof. Dr. Claus Jacob
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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