Please use this identifier to cite or link to this item: doi:10.22028/D291-28889
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Title: Enhanced adhesion of Streptococcus mutans to hydroxyapatite after exposure to saliva
Author(s): Spengler, Christian
Thewes, Nicolas
Nolle, Friederike
Faidt, Thomas
Umanskaya, Natalia
Hannig, Matthias
Bischoff, Markus
Jacobs, Karin
Language: English
Title: Journal of Molecular Recognition
Volume: 30
Issue: 7
Publisher/Platform: Wiley-Blackwell - STM
Year of Publication: 2017
Publikation type: Journal Article
Abstract: Streptococcus mutans cells form robust biofilms on human teeth and are strongly related to caries incidents. Hence, understanding the adhesion of S. mutans in the human oral cavity is of major interest for preventive dentistry. In this study, we report on atomic force microscopy-based single-cell force spectroscopy measurements of S. mutans cells to hydroxyapatite surfaces. We observe for almost all measurements a significant difference in adhesion strength for S. mutans as well as for Staphylococcus carnosus cells. However, the increase in adhesion strength after saliva exposure is much higher for S. mutans cells compared to S. carnosus cells. Our results demonstrate that S. mutans cells are well adapted to their natural environment, the oral cavity. This ability promotes the biofilm-forming capability of that species and hence the production of caries-provoking acids. In consequence, understanding the fundamentals of this mechanism may pave a way towards more effective caries-reducing techniques.
DOI of the first publication: 10.1002/jmr.2615
Link to this record: hdl:20.500.11880/27769
ISSN: 1099-1352
Date of registration: 13-Sep-2019
Faculty: NT - Naturwissenschaftlich- Technische Fakultät
M - Medizinische Fakultät
Department: NT - Physik
M - Zahn-, Mund- und Kieferheilkunde
Professorship: NT - Prof. Dr. Karin Jacobs
M - Prof. Dr. Matthias Hannig
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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