Please use this identifier to cite or link to this item: doi:10.22028/D291-21652
Title: How can we measure endometriosis-associated pelvic pain?
Author(s): Gerlinger, Christoph
Schumacher, Ulrike
Wentzeck, René
Uhl-Hochgräber, Kerstin
Solomayer, Erich-Franz
Schmitz, Heinz
Faustmann, Thomas
Seitz, Christian
Language: German
Year of Publication: 2012
OPUS Source: In: Journal of endometriosis. - 4. 2012, 3, S. 109-116
DDC notations: 610 Medicine and health
Publikation type: Journal Article
Abstract: Purpose: The aim of our work was to explore which of the most commonly used pain scales is best suited to assess treatment success in endometriosis therapy and, therefore, qualifies best to be used as primary endpoint for clinical studies in this indication. Methods: We compared patient‘s responses on the different pain scales Visual Analog Scale, Biberoglu and Behrman Score, and SF-36 Bodily Pain Subscale with the Clinical Global Impression score. Parametric and non-parametric correlation coefficients and effect sizes were calculated. Results: A total of 428 patients with endometriosis-associated pelvic pain from three studies were included in our analyses. Their mean age was 31.4±6.3years and their mean pain score on the visual analog scale was 58.1±21.9 at baseline. The highest correlation with the Clinical Global Impression score was observed for the visual analog scale followed by the B&B pelvic pain item. The highest effect sizes were found for dysmenorrhea and SF-36 bodily pain subscale followed by the visual analog scale. Conclusions: A general measure of endometriosis-related pain can be recommended as primary endpoint in clinical trials to assess painful symptoms of endometriosis. In addition, a disease-specific quality of life tool is recommended to help interpret impact on patients‘ daily activities.
Link to this record: urn:nbn:de:bsz:291-scidok-49794
Date of registration: 15-Apr-2013
Faculty: M - Medizinische Fakultät
Department: M - Frauenheilkunde
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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